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That short activity window is part of why once-daily dosing is often used in educational references—one consistent daily pulse can be enough to support a physiologic-style rhythm, especially when paired with steady sleep timing and nutrition consistency (since sleep, meal timing, and training load can all influence GH signaling day to day)

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Finally, omega-3 FAs improved the antioxidant defence (by increasing glutamate-cysteine ligase, Nrf2, glutathione synthetase and glutathione peroxidase-4 proteins) in astrocytes treated with hydrogen peroxide, and Nrf2 activation was dependent on the proportion of DHA to EPA incorporated into the membrane phospholipids [95]