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Thus, sulforaphane suppresses the cobalt chloride-induced upregulation of TLR4 by inhibiting PI3K/Akt activation and the subsequent nuclear accumulation and transcriptional activation of HIF-1α [88]
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Acetate, propionate, and butyrate are the primary short-chain fatty acids (SCFAs) found in human feces, typically in a molar ratio ranging from 3:1:1 to 10:2:1