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To explore trial participation: Search clinicaltrials.gov for "cagrilintide" or "CagriSema" to find currently enrolling trials Verify enrollment criteria (BMI, comorbidities, prior weight loss attempts, contraindications) Contact the trial site listed in the registry Discuss with your current clinician whether trial participation makes sense given your health profile If trial participation is not feasible or you do not match enrollment criteria, currently available alternatives include: FDA-approved semaglutide (Wegovy) for similar mechanism without the amylin component FDA-approved tirzepatide (Zepbound) for greater mean weight loss Older amylin pathway option: pramlintide (Symlin), FDA-approved for diabetes, used off-label rarely for weight loss Do not source cagrilintide from unauthorized suppliers

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