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13 , 14 NPs are the particularly promising drug delivery platform, which possesses the superiority that easily modulated intrinsic properties through controlling chemical synthesis, greatly improved delivery efficiency through overcoming the biological barrier to reach the lesion area, the excellent properties of biocompatibility, and minimal immunogenicity and side effects

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2,8–14 Although no experimental research to date has demonstrated disease prevention from GSH supplementation or other strategies to specifically increase GSH, observational research suggests increased dietary glutathione intake has been associated with reduced risk for oral cancer