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Protection and Healing in the Digestive System and Other Tissues: Novel Factors, Mechanisms, and Pharmaceutical Targets | Frontiers Research Topic

As a dual amylin and calcitonin receptor agonist, cagrilintide’s mechanism of action centers on binding to the calcitonin receptor (CTR) and the amylin receptor subtypes AMY₁R, AMY₂R, and AMY₃R – each formed by the CTR partnered with receptor-activity modifying proteins RAMP1, RAMP2, or RAMP3, respectively

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Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus

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