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This disease causes insufficient cardiac output, resulting in an enlarged heart.[ref] People with Keshan cardiomyopathy have low selenium concentrations in their blood, causing a lower amount of glutathione peroxidase 1.[ref] Keshan’s disease is named for a region in China where selenium deficiency is very common

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Reducing Oxidative Stress As we age, our natural production of glutathione declines, leading to increased oxidative stress