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PDF) Determination of total glutathione in cell lysates by high performance liquid chromatography with O-phthalaldehyde precolumn derivatization in the presence of tris(2-carboxyethyl)-phosphine

Shibatani T

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Although serum glutamine is not significantly altered between healthy controls and patients with steatohepatitis, serum glutamate, a metabolite which metabolic pathways are closely related to glutamine, is augmented in patients with steatohepatitis ( Hepatic glutamine metabolism is mostly regulated by the actions of the glutaminase enzyme ( GLS2 expression, the liver type glutaminase, is decreased in steatohepatitis ( Figure 1B )